Vesantech Sulforaphane Longevity Booster 60 capsules

What is Sulforaphane and how does it work?

Sulforaphane is an isothiocyanate  – the key to cell regeneration – a compound formed by chewing, crushing or digesting cruciferous vegetables (broccoli, cabbage, kale, rocket). It is formed from the precursor glucoraphanin thanks to the enzyme myrosinase.

➡️ The richest source is young broccoli sprouts (up to 20–50× more sulforaphane than a mature plant).

Sulforaphane combines the most powerful activators of longevity genes (Nrf2, SIRT1, FOXO3) with precisely selected antioxidants and micronutrients that act synergistically at the level of mitochondria, DNA and cell membranes.  Sulforaphane is one of the best-researched bioactive compounds in the field of longevity, detoxification and epigenetic DNA protection. It protects cells from aging through an anti-glycation mechanism, sulforaphane also acts as a „longevity gene switch“ and an activator of detoxification enzymes.

This cutting-edge formulation with sulforaphane activates the cells' defence system, increases the production of glutathione and stimulates detoxification enzymes that protect the body from oxidative stress and premature aging, and activates cell defence, i.e. the natural protective mechanisms of cells and processes related to cellular defence capacity.

Our sulforaphane comes from two sources – namely a patented combination of 400 mg of bioactive broccoli extract containing, in the daily dose, glucoraphanin together with myrosinase, which according to a clinical study exceeds similar products on the market by up to 25 times and 200 mg of standardised BroccoPhane® - the active form of sulforaphane. These products  are converted in the body into biologically active sulforaphane, the most powerful natural activator of the Nrf2 pathway, through which the body switches on its own antioxidant defence (glutathione, catalase, superoxide dismutase).

In the daily dose of the longevity booster, 2 capsules provide the equivalent of 17.4 mg of active sulforaphane, and 3 capsules provide 25.2 mg of pure sulforaphane.

How much pure sulforaphane per day makes sense?

Preventive / longevity dose: approx. 5–10 mg of sulforaphane per day

Stronger functional dose:  approx. 10–20 mg of sulforaphane per day

Thanks to the enteric-coated capsule form, which protects the ingredients from stomach acid, and the simultaneous presence of the enzyme myrosinase, the conversion of glucoraphanin into active sulforaphane takes place directly in the small intestine, maximising bioavailability.

The most important benefits of Sulforaphane

✅ Activates natural cellular detoxification   
✅ Protects DNA and mitochondria from damage   
✅ Supports immunity, heart, blood vessels and a long life   
✅ Reduces oxidative stress and inflammation   

Would you like to know in more detail why scientists talk about the miracle of broccoli?
Read our detailed article where we explain its precise mechanisms: A discovery ahead of its time: How sulforaphane from broccoli is changing modern medicine.
 

Average plasma sulforaphane concentration  over 48 hours from our patented premix compared to standard glucoraphanin .

Result: deep detoxification, cell and tissue regeneration, reduction of oxidative stress and inflammation.

For comprehensive cell protection, Vesantech Sulforaphane Longevity Booster is enriched with:

R-alpha-lipoic acid Bio-Enhanced® – a mitochondrial „switch“.  R-ALA is a universal antioxidant that acts in both water- and fat-soluble environments. It restores glutathione, recycles vitamins C and E, and protects mitochondria from aging. ➡️ It supports the direct production of energy in the form of adenosine triphosphate (ATP) and slows down glycation – the process that damages cellular proteins and accelerates aging.

Selenium (L-selenomethionine) – protector of DNA and a shield against oxidative stress - in the form of L-selenomethionine supports the enzymes glutathione peroxidase and thioredoxin reductase, which protect DNA, mitochondria and liver cells from damage. ➡️ It improves immunity and helps neutralise heavy metals.

Vitamins D3 + K2 – harmony of the heart, bones and immunity. This synergistic pair works as an epigenetic regulator of more than 2,000 genes.

Vitamin D3 (2,000 IU) strengthens immunity, regeneration and hormonal balance. Vitamin K2 (MK-7) ensures that calcium stays in the bones and not in the blood vessels. ➡️ Together they create a metabolic and cardiovascular shield – the foundation of a long and healthy life. They maintain balance between immune activity and cardiovascular health.

Vesantech Sulforaphane Longevity Booster represents a new approach to anti-aging nutrition – not cosmetic, but cellular. The combination of glucoraphanin with myrosinase and BroccoPhane® releases active sulforaphane, as we mentioned, an activator of the pathway Nrf2, which triggers the body's own antioxidant and detoxification response. Together, these substances create comprehensive cellular protection, activate longevity genes (Nrf2, SIRT1, FOXO3) and support long-term health at all levels – from mitochondria to the immune system.

• Activation of longevity genes (Nrf2, SIRT1, FOXO3)
• Anti-tumour action, significant especially in prevention, as documented by clinical studies
• Protection against oxidative stress and inflammation, improved mitochondrial function and cell detoxification
• Support for immunity, the cardiovascular and nervous systems
• Prevention of premature cell aging

Vesantech Sulforaphane Longevity Booster is designed for those who don't just want to live longer, but to live healthily, vitally and consciously.

Why is sulforaphane said to be the „silent guardian of cells“?

Imagine that your body is like a city full of millions of houses – cells. Every day, small sparks fly around them – free radicals, which are generated by breathing, stress, medication, smoking or toxins. If the city has too few firefighters (antioxidants), the sparks will start a fire – that's the oxidative stress that destroys DNA, proteins and cell walls. 
And when such damage repeats, a cell can „break down“ – and that is exactly the start of aging, inflammation, and above all, cancer.

Sulforaphane from broccoli is like a fire chief - acting as the „BOSS of antioxidants“, who gives the order to hundreds of protective units in the body – activating genes that produce the body's own enzymes to „put out the fire“ (e.g. glutathione, catalase, superoxide dismutase). Unlike ordinary antioxidants, which only „put out a single spark“, sulforaphane dramatically increases the number of firefighters throughout the whole city – and for days at a time!

That is why scientists consider it the most powerful natural defence mechanism against oxidative damage, aging and cancer.

Does sulforaphane lower blood sugar?

Yes, in people with impaired glucose regulation the data are favourable. Randomised studies with broccoli sprout extract (rich in sulforaphane) found a reduction in fasting glucose and HbA1c in obese patients with dysregulated T2D; the mechanism is suppression of hepatic gluconeogenesis via Nrf2 and a decrease in PEPCK. It has real clinical data (especially for T2D/prediabetes). PubMed+2science.org+2

Sulforaphane vs. Helicobacter pylori

In a clinical  study in humans, in which patients were given 70 g of broccoli sprouts daily (containing 420 micromoles of glucoraphanin, a precursor of sulforaphane), its strong activity against H. pylori, including strains resistant to conventional antibiotics, was confirmed. Sulforaphane significantly reduced not only the biomarkers of colonisation by H. pylori but also the biomarkers of stomach inflammation. These values returned to their original level 2 months after the end of treatment. 

The results thus confirmed a dual mechanism of action for sulforaphane: 1. Direct bactericidal action (killing bacteria) targeting both extracellular and intracellular forms H. pylori. 2. Indirect activation of the Nrf2 pathway, which promotes the production of antioxidant and detoxification enzymes  that protect stomach tissue.

Sulforaphane vs shingles

In shingles, it acts strongly anti-inflammatory and neuroprotective. By activating the NRF2 pathway, it reduces nerve damage, regenerates nerves, dampens oxidative stress and supports tissue regeneration, which can ease the course of the infection and subsequently reduce neuropathic pain. It also strengthens antiviral immunity by activating NK cells and interferon pathways, which supports faster recovery.

Sulforaphane vs senescent cells

Substances capable of selectively inducing death in aging cells are called senolytics. These substances kill so-called zombie cells. Among the most promising senolytic compounds are curcumin, quercetin, resveratrol, epigallocatechin gallate (EGCG), and above all sulforaphane.

The revolutionary anti-aging potential of sulforaphane 

How does sulforaphane fight aging? What do we know about it so far? Research studies have confirmed that  the primary effect of sulforaphane is the activation of a protein called Nrf2. This special protein is found in every cell of the body. When activated, Nrf2 binds to the ARE (Antioxidant Response Element), which is a switch that controls the production of antioxidants in the body. So when Nrf2/ARE is activated, our body begins producing glutathione and other antioxidant and detoxification enzymes. These enzymes work to neutralise reactive oxygen species (ROS) and other harmful molecules that accumulate in cells over time. This reduces inflammation and helps protect the body against diseases that lead to aging and age-related diseases.

What do scientific studies say about the effects of Sulforaphane?

Research on sulforaphane is one of the fastest-growing areas in the prevention of lifestyle diseases. Below we present key findings from clinical and review studies.

1. Cancer prevention and therapy support

Sulforaphane shows strong chemopreventive potential. A review study confirms its effect on several types of cancer (lung, prostate, colon and breast).

• Mechanism of action: It activates the Nrf2 pathway, induces phase II enzymes and acts directly on cancer stem cells. View the study (PMC, 2023).
• Prostate cancer: A clinical study in men under active surveillance showed that consuming glucoraphanin can slow disease progression.   
  Traka et al. study (Am J Clin Nutr, 2019).
• Safety: Pure converted sulforaphane is safe at doses of 9–60 mg and has potential as a supportive therapy. Frontiers review (2023).

2. A strong antioxidant and anti-inflammatory shield

Inflammation and oxidative stress are the main causes of cell aging. Sulforaphane works here through a dual mechanism:

• Increases glutathione: It acts as a powerful inducer of phase II detoxification enzymes, thereby increasing the production of the most important cellular antioxidant. Zhang et al. study (PNAS).
• Dampens inflammation (NF-κB): It inhibits the key "switch" of inflammatory genes (NF-κB), thereby lowering levels of inflammatory markers such as CRP, IL-6 and TNF-α. Heiss et al. study (PubMed, 2001).

3. Neuroprotection and epigenetics ("DNA rejuvenation")

Sulforaphane is not just about protecting the body, but also about preserving cognitive function and a youthful cellular profile.

• Neuron protection: Studies show that sulforaphane, even at low concentrations, can stimulate the proliferation of neural stem cells (NSC) and support their differentiation into neurons (neurogenesis). Wiley study (2017).
• Epigenetic reset: It works as an HDAC (histone deacetylase) inhibitor. This means it helps "unlock" protective genes (such as P21) that would otherwise remain inactive, thereby preserving a youthful epigenetic profile of cells. Myzak et al. study (Cancer Res, 2004).

4. Helicobacter pylori and stomach health

Research confirms both a direct and indirect effect on this resilient bacterium. A study in The Journal of Clinical Investigation describes the biology of H. pylori persistence and the potential of sulforaphane in suppressing it (Blaser MJ & Atherton JC, 2004).

5. Vesantech R-ALA Bio-Enhanced®: Synergy in the fight against tumours

This „universal antioxidant“ complements the effects of sulforaphane by acting directly in the mitochondria and influencing cell behaviour.

• Anti-cancer potential: Extensive in vitro (test-tube) and in vivo (living organism) studies suggest that ALA can reduce the proliferation (uncontrolled multiplication) of tumour cells. It also positively influences processes such as autophagy, cell migration and invasion. MDPI study (2023).

? Tip for further reading on cellular longevity:
If you're fascinated by the modern anti-aging approach and want to know how the most powerful natural antioxidants can be combined for maximum effect, be sure not to miss our article: Greens and Reds 2.0: The molecular revolution is within reach – Sulforaphane and Astaxanthin are changing the rules of the game.

Dosage and use of Sulforaphane

Dosage:  
- preventive dose: 1 capsule once daily,  
- therapeutic dose: 1 capsule twice daily, (3 capsules daily for body weight over 80 kg).

The package contains 60 capsules, which corresponds to 60 daily preventive doses or 30 daily doses at the therapeutic dose.

Correct use:  
Take the capsule once or 2-3 times daily (according to the dosage above, based on your needs and health condition) together with food , ideally with breakfast or lunch, for a period of 3 months, after which it's good to take a break of 2-4 weeks and then repeat the course.

Warning: The sulforaphane complex also contains the necessary daily dose of vitamins K2+D3

Sulforaphane and high blood pressure

Information for people with high blood pressure: Sulforaphane activates NRF2,  improves endothelial function, increases NO (nitric oxide), and this physiologically tends to lead to a decrease in blood pressure, not an increase. This is a fact supported by studies. Sulforaphane is not known to raise blood pressure - quite the opposite - in most people it lowers blood pressure. In a small proportion of people, there can be a temporary change in blood pressure regulation – mainly via the nervous system, or with an unsuitable individual dosage the body's stress response (sympathetic nervous system) may be activated.  So if you have higher blood pressure, start with a lower dose and always take it with food. Gradually increase the dose so that your nervous system can get used to it. 

 

Frequently asked questions about Sulforaphane

Isn't it enough to simply eat more regular broccoli?

Unfortunately, it isn't. Regular mature broccoli from the supermarket doesn't contain enough active sulforaphane (young sprouts have up to 50 times more). Most importantly, however, normal boiling, steaming or baking completely destroys the sensitive enzyme myrosinase in broccoli. Without this enzyme, the precursor cannot be converted into effective sulforaphane in our body. Our product contains a standardised, high-dose extract with added active myrosinase, guaranteeing real cellular absorption.

Why is it recommended to take a break of 2 to 4 weeks after 3 months of use?

Sulforaphane acts as an extremely powerful "on-off switch" for our own defence genes (the Nrf2 pathway). If these genes were stimulated continuously without any break, cells could get used to this stimulus and reduce their natural sensitivity. A short break ensures that when use resumes, the body will again respond to sulforaphane with maximum effectiveness and antioxidant power.

What does it mean that the capsules are „enteric-coated“ and why is this important?

It means that the capsule is specially designed to be resistant to aggressive stomach acids. Sulforaphane, and especially the enzyme myrosinase, are very sensitive to the acidic environment of the stomach, where they would quickly degrade. Our capsule passes safely through it and only dissolves in the small intestine. That is exactly where the ideal environment exists for the ingredients to convert into pure active sulforaphane, which is immediately absorbed into the blood.

When during the day is it best to take the Booster?

Since our complex also contains fat-soluble vitamins (D3, K2) and R-ALA acid, it's essential to always take the capsule together with food to maximise its absorption. It's ideal to take it in the morning with breakfast or at lunch. Since the product acts on the mitochondria and supports the production of cellular energy (ATP), we don't recommend taking it late in the evening before bed, as it could have a mildly stimulating effect in more sensitive people.

Can I take the product if I have thyroid problems?

Broccoli and cruciferous vegetables in general contain substances (goitrogens) that, in very large amounts, can slow down the thyroid gland. That's precisely why our scientific team expertly enriched the formula with bioactive selenium (L-selenomethionine). Selenium is an absolutely key element for the proper production of thyroid hormones and directly protects the gland. However, if you take thyroid medication or have been diagnosed with a serious condition, it's always best to consult your endocrinologist before taking any new food supplement.

Ingredients and nutritional values

Ingredients: 1 enteric-coated vegan capsule contains: bioactive broccoli extract containing glucoraphanin with Myrosinase 200 mg, BroccoPhane® 0.4 % pure sulforaphane (lipo-encapsulate) 100 mg, Vesantech R-ALA Bio-Enhanced® – premium R-alpha-lipoic acid  40 mg, Selenium (L-selenomethionine) 40 µg, Vitamin D3 (cholecalciferol) 1000 IU (25 µg), Vitamin K2 (MK-7) 50 µg

1 capsule contains:

• glucoraphanin 20.38 mg, which provides approximately 8.3 mg of sulforaphane,
• BroccoPhane 100 mg, which provides approximately 0.44 mg of sulforaphane.

In total, therefore, 1 capsule contains approximately 8.7 mg of sulforaphane.

Excipients: microcrystalline cellulose, silicon dioxide, magnesium stearate

Enteric-coated capsule: hypromellose pectin, water

Warning:  Food supplement. The product is not intended for children, pregnant or breastfeeding women. Store out of reach of children. Do not exceed the recommended daily dose. The product is not intended as a substitute for a varied diet.

Best before: see packaging 

Manufacturing certification: HACCP, ISO 9001, ISO 22000, GMP